Jirongo first expressed his presidential interest in 1998.
Between 1978 and 1981 he went to Mang'u High School. He became the chairman of AFC Leopards football club in 1991. In 1992, Jirongo together with William Samoei Ruto, led the Youth for Kanu '92 (YK '92) movement supporting the then ruling KANU party ahead of the first multiparty elections in Kenya. Jirongo became an MP during the 1997 elections when he won the Lugari Constituency seat.
Two years later he fell out with KANU and was associated with the unregistered United Democratic Movement party. Nevertheless, ahead of the 2002 elections, he was appointed the Rural Development Minister. He later formed a new political party known as Kenya African Democratic Development Union (KADDU) and successfully reclaimed the Lugari Constituency seat at the 2007 elections.
In his bid to become Kenya's fourth president, he had been identified with the URP and more recently New FORD-Kenya, before formally joining the Federal Party of Kenya. Jirongo first expressed his presidential interest in 1998.
He, however, did not appear on the ballot and this, therefore, makes the first time he is on the ballot as a presidential candidate. In 2013, he vied for the Senate in 2013 but lost to Boni Khalwale. He is the United Democratic Party leader Cyrus leader, a party he is vying through and his running mate hails from Kisii.