Maranda Boys High School has been closed indefinitely.
The County Education Director ordered for the closure of the national school on Wednesday afternoon over student unrest.
The students allegedly protested over tough school rules in the institution.
Security has been tightened at the school located in Siaya County.
The incident follows similar incidents in Kisumu Girls', Ng'iya Girls' and Chalbi Boys that led to the closure of the institutions.
The school closure comes hours after Education Principal Secretary Belio Kipsang warned the students against causing unrest in schools, saying those found culpable will be treated as criminals.