An explosion Saturday at a colliery in the northern Inner Mongolia region killed 32, Xinhua news agency said.
A total of 181 people were working underground when the gas explosion struck the mine in the city of Chifeng, with 149 managing to escape.
In a separate incident, a blast occurred late Tuesday at a private mine in Qitaihe City, in northeast Heilongjiang province, trapping 22 workers, Xinhua said.
Twenty-one were confirmed dead Friday night, it said, citing provincial authorities.
Rescue efforts were hampered by debris from the blast in some of the tunnels, according to an earlier report.
China is the world's largest coal producer and deadly accidents are common.
A further 33 miners were killed in a colliery explosion on October 31 in the southwestern municipality of Chongqing, and in September at least 18 were killed in a mine blast in the northwestern Ningxia region.
Officials say the number dying annually in the country's mines has fallen substantially in the past decade, to fewer than 1,000 a year.
But some rights groups argue the actual figures are significantly higher due to under-reporting in a sector with poor oversight.