Kenya Rugby Union have confirmed the appointment.
The match, which will be played at RFUEA ground as from 4:00pm, will be the second meeting between the sides.
The first one was played on Sunday August 20, where Kenya battled to draw the visiting team on 19-19 score-line.
Hong Kong are ranked 24th, just above Kenya on World Rugby table. Kenya will reap from the tests if they emerge aggregate winners but could sink further if they lose.