Now: Blake Lively Lively met her now-husband Ryan Reynolds on the set of Green Lantern in 2011. Since then, the couple have gotten married and had three kids, all while both of them continue to kill it on the big screen. (Um, you know, like in The Age of Adaline, A Simple Favor, and The Rhythm Section?) Karwai Tang - Getty Images

Then: Leighton Meester In Blair Waldorf we trust. After making a bunch of guest appearances on TV shows from a young age, Leighton Meester got her big break starring as culture, style, and romance icon Blair Waldorf. She also had a hit with the single "Good Girls Gone Bad" and movies such as Monte Carlo, The Roommate, Country Strong, and tons more. James Devaney - Getty Images

Now: Leighton Meester Don't worry, Leighton is still the woman you know and love. Since her GG days she's starred in a bunch of other TV shows like Making History and Single Parents, just to name a few. Bonus? She's also met and married the love of her life in fellow teen icon Adam Brody, and the couple have one child together. Kevin Winter - Getty Images

Then: Ed Westwick Do we ever really get tired of this man boldly stating: I'm Chuck Bass? Answer: No, we don't. Anyways, this guy got his start playing a role in the 2006 hit movie Children of Men, and then a year later starred as the conniving (and rich) mastermind Chuck Bass. Jason Kempin - Getty Images

Now: Ed Westwick Here's what's up with this leading man in 2020: He's focused on producing while still dabbling in the acting scene every now and then. He's also got a new GF, a model named Tamara Francesconi, and yeah, they're really freakin' cute. David M. Benett - Getty Images

Then: Penn Badgley Penn got his start by making guest appearances on tons of TV shows, and then he landed a role in the iconic 2000s film John Tucker Must Die and the rest was history. Shortly after, he landed the role of smitten-with-Serena, wannabe-writer, and stereotypical Brooklynite Dan Humphrey on GG. Jamie McCarthy - Getty Images

Now: Penn Badgley ICYMI, Penn is still a major freakin' deal. Ever heard of the Netflix show You? Yeah, that main character and serial-killer guy? That's him. He's starred in tons of other hit movies, too, like Easy A. In other news, he also married singer Domino Kirke in 2017. Awww. Jim Spellman - Getty Images

Then: Chace Crawford Swoon. Chace Crawford, aka the much-underestimated Nate Archibald, had the key to all of our hearts. While he made a few appearances in his early acting days, Gossip Girl was preeetty much his first time in any kind of spotlight. Theo Wargo - Getty Images

Now: Chace Crawford Nowadays, Chace is still out there acting. He's starred in a bunch of different shows like Blood & Oil, Casual, and The Boys, and he'll soon be appearing in the 2020 thriller Inheritance alongside Lily Collins. Taylor Hill - Getty Images

Then: Taylor Momsen Taylor Momsen started her acting career super young. Remember her in all your childhood faves? She appeared in Spy Kids 2, Underdog, Saving Shiloh, and, most notably, she was *the* Cindy Lou Who in How The Grinch Stole Christmas. Then, in 2007, the world came to know her as the unassuming drama-starter and aspiring designer Jenny Humphrey. Patrick McMullan - Getty Images

Now: Taylor Momsen Taylor's been focusing on her music ever since leaving Gossip Girl. She's the lead singer of the band The Pretty Reckless, and has been filming tons of songs for her followers during the pandemic. Instagram

Then: Jessica Szohr Jessica was making all kinds of television appearances before landing the role of Dan's intellectual, grounded BFF Vanessa Abrams on Gossip Girl. Fans couldn't help but love the no-B.S. energy she brought to the show (and TBH, the chemistry between her and Dan was real). Patrick McMullan - Getty Images

Now: Jessica Szohr Jessica is dabbling in all kinds of TV series now that her GG days are over. You can find her starring and making appearances in shows like Shameless, The Orville, Twin Peaks, and more. Rodin Eckenroth - Getty Images

Then: Connor Paolo Born in New York City, Connor trained to be an actor and performer all throughout high school. He landed tons of mini-gigs as guest stars on popular TV shows, but finally got the chance to be the troubled baby brother Eric van der Woodsen in 2007. Patrick McMullan - Getty Images

Now: Connor Paolo After becoming ~kind of a big deal~ from his GG stint, Connor eventually left the show to focus on his role in another hit series, Revenge. Since then, he's still been focusing on his acting career, specifically when it comes to the TV biz. Joshua Blanchard - Getty Images

Then: Michelle Trachtenberg Michelle Trachtenberg was the epitome of a child actressshe'd been appearing in commercials and TV shows since the age of three. You'll find her in big-time hits like Ice Princess, Harriet The Spy, 17 Again, Buffy The Vampire Slayer and, yes, as mean girl Georgina Sparks in Gossip Girl. Patrick McMullan - Getty Images

Now: Michelle Trachtenberg Michelle has certainly kept herself busy since her Gossip Girl days. She's still doing all kinds of acting, including voice acting on shows like Robot Chicken and Human Kind Of. Rodin Eckenroth - Getty Images

Then: Kristen Bell You know the ominous-yet-soothing-AF voice of Gossip Girl that we never actually saw until the end of the series? Yep, Kristen Bellan icon since her Veronica Mars dayswas the Gossip Girl voiceover. Michael Tran - Getty Images

Now: Kristen Bell Kristen's work as a voiceover legend didn't stop at Gossip Girl. ICYMI, she's also played insanely successful characters in animated movies like Frozen! Not to mention she just wrapped up the final season of The Good Place, her super-popular series on NBC. Jim Spellman - Getty Images

Then: Kelly Rutherford Before she was Lily van der Woodsen, Kelly played major roles on shows like Melrose Place. Then, in 2007, she finally became the world's most famous Upper East Side mom. Michael Tran - Getty Images

Now: Kelly Rutherford Kelly's work certainly did not end once her time playing Lily came to a close. Since then, she's starred on shows like Dynasty, Pretty Little Liars, Saving Mary Jane and more. Santiago Felipe - Getty Images

Then: Matthew Settle Rufus Humphrey was known for three things: loving Lily van der Woodsen, being in a band, and making some killer waffles. He'd been an actor for ages before playing Rufus, but it's still pretty much his most well-known role. Jason Kempin - Getty Images

Now: Matthew Settle Matthew did a few TV movies and the thriller Ouija, but for the most part, he's been majorly focusing his energy on his family and laying low. Nothing wrong with taking a little R&R! Monica Schipper - Getty Images

Then: Zuzanna Szadkowski Zuzanna is best known for playing the Waldorf family's biggest supporter, Dorota. But before that, she also held roles on The Sopranos and Law & Order. That said, I want all of you to be honest. Who thought Dorota miiiight've been Gossip Girl? *slowly raises hand* Patrick McMullan - Getty Images

Now: Zuzanna Szadkowski Zuzanna has dabbled in the theatre game since ending the GG series. She's starred in a bunch of off-Broadway productions while also appearing on TV shows such as Girls, The Good Wife, and Search Party. Jamie McCarthy - Getty Images

Then: Margaret Colin Eleanor Waldorf was the fashion designer we all wanted to be and owner of pretty much the most amazing home in all of New York. But hey, did you know Margaret wasn't cast for the show until after the pilot? Neilson Barnard - Getty Images

Now: Margaret Colin Margaret is still making all the acting moves. She's had recurring roles on hit shows like Veep, Shades of Blue and more. Bruce Glikas - Getty Images

Then: Kaylee DeFer Remember the meddling van der Woodsen "family member" Ivy Dickens? Well, she was played by Kaylee DeFer, who also starred in tons of other late-2000s hits like How I Met Your Mother and Flicka. Jean Baptiste Lacroix - Getty Images

Now: Kaylee DeFer Now, Kaylee DeFer calls herself a "former actress." She's focused on being with her family and lives in Tucson, Arizona. Instagram

Then: Katie Cassidy Before playing the manipulative Juliet Sharp on Gossip Girl, Katie Cassidy was known as a scream queen, starring in horror films like When a Stranger Calls and Black Christmas (2006). Fame is in her DNAher father is the late David Cassidy of The Partridge Family! Jon Kopaloff - Getty Images

Now: Katie Cassidy These days, Katie stars as Laurel Lance in the television series Arrow and has reprised that role in other DC Comics offerings like The Flash and DC's Legends of Tomorrow. Paul Archuleta - Getty Images

Then: Willa Holland Remember Jenny's suuuper problematic friend Agnes? That's Willa. In addition to reaching stardom via Gossip Girl, Willa was also featured on shows like The O.C. and starred in the Judy Blume movie remake of Tiger Eyes. Bobby Bank - Getty Images

Now: Willa Holland It's a Gossip Girl mini-reunion! Willa plays Thea Queen on Arrow alongside fellow GG alum Katie Cassidy. Mike Coppola - Getty Images

Then: Elizabeth Hurley Elizabeth played the super-intimidating editor-in-chief of the fictional New York Spectator (and love interest of Nate Archibald) Diana Payne in Gossip Girl, blessing our TVs with her amazing accent for the show's fifth season. Eamonn McCormack - Getty Images

Now: Elizabeth Hurley Liz's success didn't stop (or begin) at Gossip Girl. She went on to star in the hit shows The Royals and Runaways. And oh yeah, she also posts tons of amazing pics on her IG . Slaven Vlasic - Getty Images

Then: Sebastian Stan Playing bad boy Carter Baizen was one of Sebastian's first major roles. He also starred in the series Once Upon A Time around the same time as his GG appearances. Patrick McMullan - Getty Images

Now: Sebastian Stan Now, Sebastian Stan is a major name in Hollywood. He's got huge roles in Marvel films like Captain America, Avengers, and in others like Logan Lucky, I Tonya, The Martian, and more. We can't keep up! Paras Griffin - Getty Images

Then: Wallace Shawn Wallace has been acting since the late '60s. His stint on Gossip Girl, while much-loved by fans, was nothing new to him. He'd already played characters in major movies like Toy Story (Rex!), Family Guy, Star Trek, The Haunted Mansion, The Incredibles, and more. Patrick McMullan - Getty Images

Now: Wallace Shawn Wallace hasn't stopped acting. You can find him in more recent hits like Marriage Story, Young Sheldon, and Search Party, just to name a few! Jean Baptiste Lacroix - Getty Images